Switching to CABENUVA

Liver problems. Liver problems have happened in people with or without history of liver problems or other risk factors. Your healthcare provider may do blood tests to check your liver function. People with a history of liver problems or people who have certain liver function test changes may have an increased risk of developing new or worsening changes in certain liver tests during treatment with CABENUVA. Call your healthcare provider right away if you develop any of the following signs or symptoms of liver problems: the skin or the white part of the eyes turns yellow (jaundice); dark or “tea-colored” urine; light-colored stools (bowel movements); nausea or vomiting; loss of appetite; pain, aching, or tenderness on the right side of the stomach area; itching.

Before receiving CABENUVA

Tell your healthcare provider about all your medical conditions, including if you:

have ever had a skin rash or an allergic reaction to medicines that contain cabotegravir or rilpivirine.

have ever had liver problems, including hepatitis B or C infection.

have or ever had kidney problems.

have ever had mental health problems.

are pregnant or plan to become pregnant. It is not known if CABENUVA will harm your unborn baby. CABENUVA can remain in your body for up to 12 months or longer after the last injection.

are breastfeeding or plan to breastfeed. CABENUVA may pass into your breast milk. Talk to your healthcare provider about risks to your baby from breastfeeding during or after treatment with CABENUVA.

How will I receive CABENUVA?

Once a month or once every 2 months, a healthcare provider will inject CABENUVA as 2 injections (cabotegravir and rilpivirine), into the muscle of your buttocks.

Before receiving your first CABENUVA injections, your healthcare provider may have you take 1 VOCABRIA (cabotegravir) tablet and 1 EDURANT (rilpivirine) tablet once a day for 1 month (at least 28 days) to assess how you tolerate these medicines.

Stay under the care of a healthcare provider during CABENUVA treatment. It is important that you attend all planned injection appointments.

If you miss or plan to miss a scheduled CABENUVA injection by more than 7 days, call your healthcare provider right away to discuss your treatment options.

If you stop treatment with CABENUVA you will need to take other medicines to treat your HIV-1 infection and reduce the risk of developing viral resistance. Call your healthcare provider right away to discuss your treatment options.